methyl (S)-lactate → HCID 54052357, compound

Participants

Reaction Steps

Prepared from of 4-(benzo[b]naphtho[2,3-d]thiophen-11-yl)-2,6-diiodo-phenol (Example 26) and commercially available (S)-lactic acid, methyl ester. White solid: mp 134-136: NMR (CDCl3): δ8.38 (s, 1 H), 7.95 (dd J=8, 6 Hz, 1 H), 7.93 (d, J=1 Hz, 2 H), 7.81 (d, J=8 Hz, 1 H), 7.58 (ddd, J=8, 7, 1 Hz, 1 H), 7.59-7.54 (m, 2 H), 7.49-7.40 (m, 2 H), 7.15(ddd, J=8, 7, 1 Hz, 1 H), 6.77 (d, J=8, 1 Hz, 1 H), 5.48 (q, J =7 Hz, 1 H), 1.82 (d, J=7 Hz, 2 H); MS (+FAB): [M+H]+, 651; Anal. Calc. for C26H16I2O3S: C, 46.18, H, 2.48, N, 0.00. Found: C, 46.60, H, 2.50, N, 0.21.

Provenance & Evidence