Bromine → HCID 18687869, compound

Participants

Reaction Steps

Prepared from 2,6-dibromo-4-(6-bromo-benzo[b]naphtho [2,3-d]thiophen- 1 -yl)-phenol (Example 21) and 3-pyridin-3-yl-propionic acid, ethyl ester (Example 104). White solid: NMR (DMSO-d6); δ8.98 (s, 1 H), 8.82 (d., J=5 Hz, 1 H), 8.57 (d, J=8 Hz, 1 H), 8.28 (d, J=8 Hz, 1 H), 8.07 (d, J=8 Hz, 1 H), 7.96 (dd, J=8, 6 Hz, 1 H), 7.82 (d, J=2 Hz, 1 H), 7.79 (m, 1 H), 7.78 (d, J=2 Hz, 1 H),7.62 (dd, J=8, 1 Hz, 1 H), 7.57-7.50 (m, 2 H), 7.27 (dd, J=8, 1 Hz, 1 H), 6.67 (d, J=8 Hz, 1 H), 5.45 (dd, J=6, 2, 1 H), 3.60 (m, 2 H); MS (+FAB): [M+H]+, 3 bromine isotope pattern, 710, 712, 714, 716; Anal. Calc. for C30H18Br3NO3S.HCl: C, 48.13, H, 2.56, N, 1.87. Found: C, 48.12, H, 2.86, N, 1.65.

Provenance & Evidence