Bromine → HCID 21970371, compound

HRID 1873185Notes

Reaction equation

HRID 1873185 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:18]4[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=4[S:20][C:16]=3[C:15]([Br:25])=[C:14]3[C:9]=2[CH:10]=[CH:11][CH:12]=[CH:13]3)=[CH:4][C:3]=1[OH:26].[C:27]([O:32]C)(=[O:31])[C@@H:28]([CH3:30])O.BrBr>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:18]4[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=4[S:20][C:16]=3[C:15]([Br:25])=[C:14]3[C:9]=2[CH:10]=[CH:11][CH:12]=[CH:13]3)=[CH:4][C:3]=1[O:26][C@H:28]([CH3:30])[C:27]([OH:32])=[O:31]

Participants

4

Reactant 3

HCID 24408BromineHCID 637514(+)-Methyl lactateHCID 18687792HCID 18687792, compound

Product 1

HCID 21970371HCID 21970371, compound

Procedure

Prepared from of 2-bromo-5-(6-bromo-benzo[b]naphtho[2,3-d]thiophen- 11-yl)-phenol (Example 68) and commercially available (R)-lactic acid, methyl ester. White solid: mp 133-134.5° C.: MS (-ESI): [M-H]-, 2 bromine isotope pattern 553, 555, 557; Anal. Calc. for C25H16Br2O3S: C, 53.98, H, 2.90, N, 0.00. Found: C, 53.18, H, 2.82, N, 0.04.

Sources & evidence

ORD record
ord-f91f1f02bf76400c891e9f8f80ca8c85
Source dataset
uspto-grants-2000_08
Patent number
US06110962

Reaction notes

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