2-Mercaptobenzoic Acid → HCID 15480017, compound

HRID 1873226Notes

Reaction equation

HRID 1873226 reaction equation
N[C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:12])[C:9]([OH:11])=[O:10])=[CH:4][C:3]=1[CH2:13][C:14]([OH:16])=[O:15].[C:17]([OH:26])(=[O:25])[C:18]1[C:19](=[CH:21][CH:22]=[CH:23][CH:24]=1)[SH:20]>>[C:14]([CH2:13][C:3]1[CH:4]=[C:5]([CH:8]([CH3:12])[C:9]([OH:11])=[O:10])[CH:6]=[CH:7][C:2]=1[S:20][C:19]1[CH:21]=[CH:22][CH:23]=[CH:24][C:18]=1[C:17]([OH:26])=[O:25])([OH:16])=[O:15]

Participants

3

Reactant 2

HCID 54432-Mercaptobenzoic AcidHCID 11138738HCID 11138738, compound

Product 1

HCID 15480017HCID 15480017, compound

Procedure

2-(4-Amino-3-carboxymethylphenyl)propionic acid or its salt is diazotized in the same manner as in Preparation-I, and the resulting compound (i.e., diazo compound) is reacted with thiosalicylic acid at 0 to 100° C., preferably under basic conditions, to give the 2-[3-carboxymethyl-4-(2-carboxyphenylthio)phenyl]propionic acid or its salt.

Sources & evidence

ORD record
ord-ba1b2897f1eb48f4ac20d9794b912c21
Source dataset
uspto-grants-2000_08
Patent number
US06111115

Reaction notes

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