HuagongsheHuagongshe Chemistry Print Report · For research reference only
7,8-difluoro-2-pentyl-2H-chromene → 7,8-Difluoro-2-pentyl-3,4-dihydro-2H-1-benzopyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7,8-difluoro-2-pentyl-2H-chromene | HCID 59215273 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 7,8-Difluoro-2-pentyl-3,4-dihydro-2H-1-benzopyran | HCID 23115727 | — |
Reaction Steps
51.0 g (0.21 mol) of 7,8-difluoro-2-pentyl-2H-chromene are hydrogenated at RT for 1 h in 510 ml of toluene in the presence of Pd/C (5% of Pd). The batch is evaporated to dryness: the crude product (yellowish liquid) can be used directly for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08303844B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-39843891419c41f6acc794de2578ff4d |
| Source note | uspto-grants-2012_11 |