Potassium Carbonate → HCID 59161013, compound

Participants

Reaction Steps

5.00 g (12.44 mmol) of the compound from Example 20A are dissolved in 57 ml of acetonitrile, and 4.51 g (24.89 mmol) of 3-bromopropyl acetate and 3.44 g (24.89 mmol) of potassium carbonate are added. The reaction mixture is stirred at +80° C. for 8 h. After filtration, the solvent is removed on a rotary evaporator. The residue is taken up in 50 ml of ethyl acetate and washed in each case once with 10 ml of water and 10 ml of saturated aqueous sodium bicarbonate solution. The organic phase is dried over magnesium sulfate and the solvent is removed on a rotary evaporator. The crude product is used in the next reaction without further purification.

Provenance & Evidence