Methyl morpholine oxide → HCID 59161047, compound

Participants

Reaction Steps

1.36 g (6.30 mmol) of the compound from Example 27A are dissolved in 14 ml dry dichloromethane, and 3.39 g of molecular sieve (4 Å), 1.11 g (9.44 mmol) of N-methylmorpholine N-oxide and 111 mg (0.32 mmol) of tetrapropylammonium perruthenate are added in succession. The reaction mixture is stirred at RT for 1 h and then directly purified chromatographically on silica gel 60 (mobile phase: gradient dichloromethane/ethanol 100:1→10:1).

Provenance & Evidence