HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazin-2-one → 4-{3-[5-(2-Fluoro-phenyl)-thiophen-2-yl]-acryloyl}-piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazin-2-one | HCID 231360 | — |
| Reactant | HCID 53412006 | HCID 53412006 | — |
| Product | 4-{3-[5-(2-Fluoro-phenyl)-thiophen-2-yl]-acryloyl}-piperazin-2-one | HCID 68537959 | — |
Reaction Steps
The compound was prepared analogously to Example 4(b) using 150 mg (0.6 mmol) of 3-[5-(2-fluoro-phenyl)-thiophen-2-yl]-acrylic acid and 54.2 mg (0.54 mmol) of piperazin-2-one. Yield: 109 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304438B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-69788ef9ea864ee8b837e43bea7dcfd1 |
| Source note | uspto-grants-2012_11 |