Succinimide → HCID 25116071, compound

HRID 1873779Notes

Reaction equation

HRID 1873779 reaction equation
Cl[CH2:2][C:3]([N:5]1[CH2:10][CH2:9][CH:8]([N:11]2[C:15](=[O:16])[C:14]([CH3:18])([CH3:17])[C:13]([C:19]3[C:24]4[CH2:25][C:26]([CH3:29])([CH3:28])[O:27][C:23]=4[C:22]([O:30][CH3:31])=[CH:21][CH:20]=3)=[N:12]2)[CH2:7][CH2:6]1)=[O:4].[C:32]1(=[O:38])[NH:36][C:35](=[O:37])[CH2:34][CH2:33]1>>[CH3:31][O:30][C:22]1[C:23]2[O:27][C:26]([CH3:29])([CH3:28])[CH2:25][C:24]=2[C:19]([C:13]2[C:14]([CH3:17])([CH3:18])[C:15](=[O:16])[N:11]([CH:8]3[CH2:7][CH2:6][N:5]([C:3](=[O:4])[CH2:2][N:36]4[C:32](=[O:38])[CH2:33][CH2:34][C:35]4=[O:37])[CH2:10][CH2:9]3)[N:12]=2)=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 11439SuccinimideHCID 66616513HCID 66616513, compound2×

Product 1

HCID 25116071HCID 25116071, compound

Procedure

Prepared analogously as described for example 1 using 2-[1-(chloroacetyl)piperidin-4-yl]-5-(7-methoxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-4-yl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one (compound A5) and succinimide as starting compounds.

Workup

  1. customPrepared analogously

Sources & evidence

ORD record
ord-be427ebd7f61424980a26f3b488e0530
Source dataset
uspto-grants-2012_11
Patent number
US08304436B2

Reaction notes

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