Succinimide → HCID 66616624, compound

HRID 1873780Notes

Reaction equation

Cl[CH2:2][C:3]([N:5]1[CH2:10][CH2:9][CH:8]([N:11]2[C:15](=[O:16])[C:14]([CH3:18])([CH3:17])[C:13]([C:19]3[C:24]4[CH2:25][C:26]5([O:31][C:23]=4[C:22]([O:32][CH3:33])=[CH:21][CH:20]=3)[CH2:30][CH2:29][CH2:28][CH2:27]5)=[N:12]2)[CH2:7][CH2:6]1)=[O:4].[C:34]1(=[O:40])[NH:38][C:37](=[O:39])[CH2:36][CH2:35]1>>[CH3:33][O:32][C:22]1[C:23]2[O:31][C:26]3([CH2:27][CH2:28][CH2:29][CH2:30]3)[CH2:25][C:24]=2[C:19]([C:13]2[C:14]([CH3:18])([CH3:17])[C:15](=[O:16])[N:11]([CH:8]3[CH2:9][CH2:10][N:5]([C:3](=[O:4])[CH2:2][N:38]4[C:34](=[O:40])[CH2:35][CH2:36][C:37]4=[O:39])[CH2:6][CH2:7]3)[N:12]=2)=[CH:20][CH:21]=1

Participants

Reactant 2

HCID 11439Succinimide

HCID 66616562HCID 66616562, compound2×

Product 1

HCID 66616624HCID 66616624, compound

Procedure

Prepared analogously as described for example 1 using 2-[1-(chloroacetyl)piperidin-4-yl]-5-(7-methoxy-3H-spiro[1-benzofuran-2,1′-cyclopentan]-4-yl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one (compound A6) and succinimide as starting compounds.

Workup

customPrepared analogously

Sources & evidence

ORD record: ord-15d492cb9a02467d9e560a7c2c39682a
Source dataset: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08304436B2

Reaction notes

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