Succinimide → HCID 25116541, compound

HRID 1873783Notes

Reaction equation

Cl[CH2:2][C:3]([N:5]1[CH2:10][CH2:9][CH:8]([N:11]2[N:15]=[C:14]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([O:24][CH3:25])[CH:17]=3)[C:13]3([CH2:29][CH2:28][CH2:27][CH2:26]3)[C:12]2=[O:30])[CH2:7][CH2:6]1)=[O:4].[C:31]1(=[O:37])[NH:35][C:34](=[O:36])[CH2:33][CH2:32]1>>[CH3:25][O:24][C:18]1[CH:17]=[C:16]([C:14]2[C:13]3([CH2:29][CH2:28][CH2:27][CH2:26]3)[C:12](=[O:30])[N:11]([CH:8]3[CH2:7][CH2:6][N:5]([C:3](=[O:4])[CH2:2][N:35]4[C:31](=[O:37])[CH2:32][CH2:33][C:34]4=[O:36])[CH2:10][CH2:9]3)[N:15]=2)[CH:21]=[CH:20][C:19]=1[O:22][CH3:23]

Participants

Reactant 2

HCID 11439Succinimide

HCID 66616445HCID 66616445, compound

Product 1

HCID 25116541HCID 25116541, compound

Procedure

Prepared analogously as described for example 1 using 2-[1-(chloroacetyl)piperidin-4-yl]-4-(3,4-dimethoxyphenyl)-2,3-diazaspiro[4.4]non-3-en-1-one (compound A10) and succinimide as starting compounds.

Workup

customPrepared analogously

Sources & evidence

ORD record: ord-fa7da16c71ff42a3b0bd03810d5f75d0
Source dataset: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08304436B2

Reaction notes

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