HCID 53629224, compound → HCID 58091491, compound

Participants

Reaction Steps

Following conditions described for Step 9 of Example 14, the acid from Step 1 of Example 92 was coupled with 2-amino-5-cyclopropylthiadiazole to give Example 93. 1H NMR (400 MHz, chloroform-d) δ ppm 1.16-1.41 (m, 10H) 2.27-2.38 (m, 1H) 2.57 (s, 3H) 3.43-3.93 (m, 8H) 4.59 (s, 1H) 7.01 (d, J=7.78 Hz, 1H) 7.51 (t, J=8.53 Hz, 3H) 7.56-7.67 (m, 2H) 8.12 (d, 2H); MS (ES+) m/z: 597 (M+H); LC retention time: 3.08 min (analytical HPLC Method B).

Provenance & Evidence