HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → (3-Methanesulfonylphenyl)hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | 3-(Methylsulfonyl)aniline hydrochloride | HCID 2735179 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Product | (3-Methanesulfonylphenyl)hydrazine | HCID 22034382 | — |
Reaction Steps
B-012 is prepared analogously to B-05 starting from 3-methylsulfonylaniline hydrochloride (2.50 g, 11.4 mmol), sodium nitrite (1.18 g, 17.1 mmol) and tin(II)chloride dihydrate (14.9 g, 66.0 mmol). The product is purified by precipitation from ethyl acetate with cyclohexane. Yield: 1.08 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304556B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-84fbf02d6f06485693273b86114eaae4 |
| Source note | uspto-grants-2012_11 |