Hydrochloric Acid → HCID 57749149, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 5-(4-chloro-3-nitrophenoxy)-2-nitropyridine (3.80 g, 12.9 mmol), reduced iron (4.84 g, 86.7 mmol), 6N hydrochloric acid (2 mL), ethanol (20 mL) and water (4 mL) was stirred at 85° C. for 2 hr. The reaction mixture was filtered through celite, and the filtrate was concentrated under reduced pressure. The residue was collected by filtration and washed with ethyl acetate-hexane to give the title compound (2.02 g, 66%) as a gray solid.

Provenance & Evidence