Iodoacetamide → HCID 68989968, compound

Participants

Reaction Steps

In the same manner as in Reference Example 5 and using N-{2-fluoro-5-[(6-{[(4-methylphenyl)sulfonyl]amino}pyridin-3-yl)oxy]phenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide (7.25 g, 14.6 mmol), N,N-diisopropylethylamine (3.31 mL, 19.0 mmol), N,N-dimethylformamide (30 mL) and iodoacetamide (3.51 g, 19.0 mmol) as starting materials, the title compound (5.86 g, 73%) was obtained as a white solid.

Provenance & Evidence