HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 57749163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Bromo-2-nitropyridine | HCID 817620 | — |
| Reactant | 1,1-Dimethylethyl N-(5-hydroxy-2-methylphenyl)carbamate | HCID 57749293 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57749163 | HCID 57749163 | 70% |
Reaction Steps
In the same manner as in Reference Example 33 and using tert-butyl (5-hydroxy-2-methylphenyl)carbamate (18.9 g, 85.0 mmol), cesium carbonate (41.8 g, 0.128 mol), N,N-dimethylformamide (100 mL) and 5-bromo-2-nitropyridine (16.4 g, 80.7 mmol) as starting materials, the title compound (19.5 g, 53%) was obtained as a pale-yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-5fd993cc21094f3fa402df2fc3e000c1 |
| Source note | uspto-grants-2012_11 |