HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-(6-nitropyridin-3-yloxy)phenylcarbamate → Tert-butyl 3-(6-aminopyridin-3-yloxy)phenylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-(6-nitropyridin-3-yloxy)phenylcarbamate | HCID 57749209 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Tert-butyl 3-(6-aminopyridin-3-yloxy)phenylcarbamate | HCID 57749334 | 106.6% |
Reaction Steps
In the same manner as in Reference Example 34 and using tert-butyl {3-[(6-nitropyridin-3-yl)oxy]phenyl}carbamate (16.4 g, 49.5 mmol), palladium carbon (50% water-containing product, 1.50 g) and methanol (100 mL) as starting materials, the title compound (15.9 g, quant.) was obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-a02cc20b73f54b1aa2c9721bf3bc5b73 |
| Source note | uspto-grants-2012_11 |