HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 57749141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Bromo-2-nitropyridine | HCID 817620 | — |
| Reactant | Tert-butyl (2-fluoro-5-hydroxyphenyl)carbamate | HCID 57749385 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57749141 | HCID 57749141 | 50% |
Reaction Steps
In the same manner as in Reference Example 33 and using tert-butyl (2-fluoro-5-hydroxyphenyl)carbamate (22.4 g, 98.4 mmol), 5-bromo-2-nitropyridine (16.7 g, 82.0 mmol), cesium carbonate (40.1 g, 123 mmol) and N,N-dimethylformamide (140 mL) as starting materials, the title compound (14.2 g, 50%) was obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-fc37d8e74ae64b44a9d6113c3309f5ac |
| Source note | uspto-grants-2012_11 |