HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isothiocyanatoformate → HCID 57749277, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isothiocyanatoformate | HCID 85320 | — |
| Reactant | HCID 57749142 | HCID 57749142 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 57749277 | HCID 57749277 | 80% |
Reaction Steps
In the same manner as in Reference Example 30 and using tert-butyl {5-[(6-aminopyridin-3-yl)oxy]-2-fluorophenyl}carbamate (9.60 g, 30.1 mmol), DMSO (60 mL) and ethyl isothiocyanatoformate (4.73 g, 36.1 mmol) as starting materials, the title compound (10.8 g, 80%) was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-eba542606b4841d981f2c0cb7c4c1406 |
| Source note | uspto-grants-2012_11 |