Sodium Hydroxide → 1092394-34-7

HRID 1874372Notes

Reaction equation

HRID 1874372 reaction equation
[CH2:1]([C:3]1[C:4]([C:9]([O:11]CC)=[O:10])=[N:5][N:6]([CH3:8])[CH:7]=1)[CH3:2].[OH-].[Na+]>C(O)C>[CH2:1]([C:3]1[C:4]([C:9]([OH:11])=[O:10])=[N:5][N:6]([CH3:8])[CH:7]=1)[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 57749118HCID 57749118, compound

Product 1

HCID 572825701092394-34-7Yield 53%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the same manner as in Reference Example 52 and using ethyl 4-ethyl-1-methyl-1H-pyrazole-3-carboxylate (460 mg, 2.50 mmol), 8N aqueous sodium hydroxide solution (620 μL) and ethanol (3 mL) as starting materials, the title compound (200 mg, 53%) was obtained as a white solid.

Sources & evidence

ORD record
ord-c8de426f2eaf45a4b72e12cbe10654f7
Source dataset
uspto-grants-2012_11
Patent number
US08304557B2

Reaction notes

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