Tetrahydrofuran → HCID 57749160, compound

Participants

Reaction Steps

In the same manner as in Example 18-4 and using 1,4-dimethyl-1H-pyrazole-3-carboxylic acid (127 mg, 0.904 mmol), tetrahydrofuran (8 mL), oxalyl chloride (86.7 μL, 0.994 mmol), N-[6-(3-aminophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (60.0 mg, 0.194 mmol), N,N-dimethylformamide (1 drop) and N,N-dimethylacetamide (3 mL) as starting materials, the title compound (57.7 mg, 69%) was obtained as a white solid.

Provenance & Evidence