Tetrahydrofuran → HCID 57749127, compound

Participants

Reaction Steps

In the same manner as in Example 18-4 and using 1,4-dimethyl-1H-pyrrole-2-carboxylic acid (225 mg, 1.62 mmol), tetrahydrofuran (7 mL), oxalyl chloride (212 μL, 1.67 mmol), N-[6-(3-aminophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (200 mg, 0.646 mmol), N,N-dimethylformamide (1 drop) and N,N-dimethylacetamide (3 mL) as starting materials, the title compound (228 mg, 82%) was obtained as a white solid.

Provenance & Evidence