HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dimethyl-3-furoyl Chloride → HCID 57749165, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dimethyl-3-furoyl Chloride | HCID 2734804 | — |
| Reactant | N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide | HCID 57749401 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57749165 | HCID 57749165 | 58.9% |
Reaction Steps
In the same manner as in Example 58 and using 2,5-dimethyl-3-furoyl chloride (84.0 μL, 0.630 mmol), N,N-dimethylacetamide (5 mL) and N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (185 mg, 0.572 mmol) as starting materials, the title compound (150 mg, 56%) was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-b48fbbc2be1c4bc19800797392839a95 |
| Source note | uspto-grants-2012_11 |