Cyclobutanecarbonyl chloride → N-[5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-methylphenyl]cyclobutanecarboxamide

Participants

Reaction Steps

In the same manner as in Example 24 and using cyclobutanecarbonyl chloride (56.0 μL, 0.489 mmol), N,N-dimethylacetamide (5 mL) and N-[6-(3-amino-4-methylphenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (140 mg, 0.433 mmol) as starting materials, the title compound (83.5 mg, 45%) was obtained as a white solid.

Provenance & Evidence