Tetrahydrofuran → HCID 57749177, compound

Participants

Reaction Steps

In the same manner as in Example 18-4 and using 1-ethyl-4-methyl-1H-pyrazole-3-carboxylic acid (150 mg, 0.970 mmol), tetrahydrofuran (7 mL), oxalyl chloride (93.0 μL, 1.07 mmol), N-[6-(3-aminophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (200 mg, 0.646 mmol), N,N-dimethylformamide (1 drop) and N,N-dimethylacetamide (5 mL) as starting materials, the title compound (150 mg, 52%) was obtained as a white solid.

Provenance & Evidence