Tetrahydrofuran → HCID 57749393, compound

Participants

Reaction Steps

In the same manner as in Example 55 and using 1-methyl-1H-pyrazole-5-carboxylic acid (46.1 mg, 0.366 mmol), tetrahydrofuran (5 mL), thionyl chloride (63.3 μL, 0.730 mmol), N,N-dimethylformamide (2 drops), N-[6-(3-amino-4-chlorophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (114 mg, 0.332 mmol) and N,N-dimethylacetamide (6 mL) as starting materials, the title compound (69.5 mg, 46%) was obtained as a white solid.

Provenance & Evidence