Tetrahydrofuran → HCID 57749086, compound

Participants

Reaction Steps

In the same manner as in Example 55 and using 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (70.8 mg, 0.365 mmol), tetrahydrofuran (5 mL), thionyl chloride (63.3 μL, 0.730 mmol), N,N-dimethylformamide (2 drops), N-[6-(3-amino-4-chlorophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (112 mg, 0.326 mmol) and N,N-dimethylacetamide (6 mL) as starting materials, the title compound (63.6 mg, 38%) was obtained as a white solid.

Provenance & Evidence