HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 57749262, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Reactant | HCID 57749155 | HCID 57749155 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 57749262 | HCID 57749262 | 47% |
Reaction Steps
In the same manner as in Example 98 and using methyl 3-[(5-aminopyridin-2-yl)oxy]benzoate (12.5 g, 51.2 mmol), potassium thiocyanate (34.8 g, 358 mmol), bromine (8.2 mL) and acetic acid (125 mL) as starting materials, the title compound (7.25 g, 47%) was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304557B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-d6952320a27343ddb88495f1682e70e4 |
| Source note | uspto-grants-2012_11 |