Tetrahydrofuran → HCID 57749107, compound

Participants

Reaction Steps

In the same manner as in Example 18-4 and using 1-methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid (194 mg, 1.00 mmol), tetrahydrofuran (7 mL), oxalyl chloride (95.6 μL, 1.10 mmol), N-[6-(3-aminophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (281 mg, 0.910 mmol), N,N-dimethylformamide (1 drop) and N,N-dimethylacetamide (5 mL) as starting materials, the title compound (211 mg, 48%) was obtained as a white solid.

Provenance & Evidence