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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 187462Generated: October 26, 2026

Water → Methyl 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-1-naphthalenecarboxylate

https://huagongshe.com/reaction/187462

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHydrofluoric AcidHCID 14917—
ReactantChlorosuccinimideHCID 31398—
Reactant1-Propene, 2-bromo-3,3,3-trifluoro-HCID 272696—
Reactant1,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzeneHCID 23159823—
ReactantMethyl 4-[(hydroxyimino)methyl]-1-naphthalenecarboxylateHCID 86645276—
ProductMethyl 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-1-naphthalenecarboxylateHCID 58338637—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c39ce10a91604130ba2581724920c68b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)