Methanol → HCID 68480779, compound

Participants

Reaction Conditions

Reaction Steps

Methyl 5-acetyl-3-chloro-1H-pyrrole-2-carboxylate (0.034 g, 0.169 mmol) was dissolved in THF (1 mL), methanol (1 mL) and 1N LiOH (1 mL). The reaction mixture was heated to 60° C. and stirred. The reaction mixture was evaporated and purification was accomplished by reverse-phase HPLC (water/acetonitrile with 0.1% TFA) to afford the title compound (0.033 g, 67%) as an impure product which was used with no further purification. LCMS: m/z 187.9 (M+1).

Provenance & Evidence