HCID 178510254, compound → HCID 178510251, compound

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The title compound was prepared in a similar manner to that described herein using 2-azido-4-chloro-N-({4-chloro-3-[(2-chloro-6-cyano-4-pyridinyl)oxy]-2-fluorophenyl}methyl)-1H-imidazole-5-carboxamide (123 mg, 0.255 mmol), a catalytic amount of Lindlar catalyst in EtOAc (15 ml) under H2 (50 psi) to afford the title compound as a white powder (52 mg, 45%). 1H NMR (400 MHz, DMSO-d6) δ ppm 10.96 (1H, s) 7.98 (1H, d) 7.78 (1H, t) 7.59 (1H, d) 7.53 (1H, d) 7.39 (1H, t) 5.83 (2H, s) 4.50 (2H, d). LCMS: m/z 455 (M+1).

Provenance & Evidence