HCID 70937102, compound → HCID 86761670, compound

Participants

Reaction Conditions

Reaction Steps

A solution of the above alcohol, MnO2 (0.42 g, 4.86 mmol) in CH2Cl2 (5 mL) was stirred at RT for 1 h. Additional MnO2 (0.42 g, 4.86 mmol) was added and the reaction mixture was heated at 40° C. overnight and then evaporated and purified by silica gel chromatography (0-35% EtOAc/hex) to afford the title compound (0.083 g, 48%) as a clear oil. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 9.93 (s, 1H), 6.00 (s, 2H), 5.33 (br. s., 1H), 3.60-3.69 (m, 2H), 2.90 (s, 3H), −0.02 (s, 9H).

Provenance & Evidence