HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrolein → HCID 86649344, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrolein | HCID 7847 | — |
| Reactant | tert-butyl 2-oxo-cyclopentanecarboxylate | HCID 11052317 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86649344 | HCID 86649344 | — |
Reaction Steps
A solution of acrolein (4.19 g; 74.83 mmoles—2.5 eq.) in 10 mL of anhydrous dichloromethane is poured, over 30 minutes, at −25° C., under argon and with slow stirring, into a solution of tert-butyl 2-oxo-cyclopentanecarboxylate (5.51 g; 29.93 mmoles) and catalyst Q (1.46 g; 2.99 mmoles—0.1 eq.) in 60 mL of anhydrous dichloromethane
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309341B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-575c926c99cb40b0b2445b87e12a15d7 |
| Source note | uspto-grants-2012_11 |