Methyl iodide → 5,6-Dimethyl-4,5-dihydro-thieno[2,3-c]pyridinium iodide

HRID 1875346Notes

Reaction equation

HRID 1875346 reaction equation
[CH3:1][CH:2]1[N:7]=[CH:6][C:5]2[S:8][CH:9]=[CH:10][C:4]=2[CH2:3]1.[CH3:11][I:12]>C(#N)C>[I-:12].[CH3:1][CH:2]1[N+:7]([CH3:11])=[CH:6][C:5]2[S:8][CH:9]=[CH:10][C:4]=2[CH2:3]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 574239795-Methyl-4,5-dihydro-thieno[2,3-c]-pyridine

Product 1

HCID 685900055,6-Dimethyl-4,5-dihydro-thieno[2,3-c]pyridinium iodide

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 4.0 g (26.5 mmol) 5-methyl-4,5-dihydro-thieno[2,3-c]-pyridine in 250 ml acetonitrile is combined at RT with 16.5 ml (264.5 mmol) methyl iodide and stirred for 30 min. The precipitate formed is filtered off and washed with acetonitrile.

Workup

  1. customThe precipitate formed
  2. filtrationis filtered off
  3. washwashed with acetonitrile

Sources & evidence

ORD record
ord-9e8eb94d090b4b9ebc5e1659be9e08e3
Source dataset
uspto-grants-2012_11
Patent number
US08309542B2

Reaction notes

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