反应详情

Prepared by treatment of (E)-3-(dimethylamino)-1-(1-ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one and 1-(3-hydroxyphenyl)guanidine hydrochloride. 1H-NMR (DMSO-d6) δ: 1.18 (t, 3H, J=7.2 Hz, CH3), 4.37 (q, 2H, J=7.2 Hz, CH2), 6.40 (m, 1H, Ph-H), 7.08 (t, 1H, J=7.6 Hz, Ph-H), 7.18 (m, 1H, Ar—H), 7.24 (d, 1H, J=5.6 Hz, Pyrimidin-H), 7.37 (s, 1H, Ph-H), 8.36 (m, 2H, Pyrimidin-H and Ar—H), 8.59 (s, 1H, Ar—H), 9.00 (d, 1H, J=8.0 Hz, Ph-H), 9.24 (s, 1H, Ar—H), 9.33 (s, 1H, NH). MS (ESI+) m/z 332.1355 (M+H)+.