反应详情

Prepared by treatment of (E)-3-(dimethylamino)-1-(1-ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one and 1-(3-cyanophenyl)guanidine hydrochloride. 1H-NMR (DMSO-d6) δ: 1.48 (t, 3H, J=7.2 Hz, CH3), 4.39 (q, 2H, J=7.2 Hz, CH2), 7.27 (m, 1H, Ar—H), 7.36 (d, 1H, J=4.4 Hz, Pyrimidin-H), 7.42 (m, 1H, Ph-H or Ar—H), 7.51 (m, 1H, Ph-H or Ar—H), 7.98 (m, 1H, Ar—H), 8.38 (m, 1H, Ph-H or Ar—H), 8.46 (m, 2H, Pyrimidin-H or Ar—H), 8.63 (s, 1H, Ar—H), 8.94 (m, 1H, Ph-H or Ar—H), 9.85 (s, 1H, NH). MS (ESI+) m/z 341.1489 (M+H)+.