(E)-1-(7-chloro-1-ethyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one → 3-(4-(7-Chloro-1-ethyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-ylamino)phenol

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Prepared by treatment of (E)-1-(7-chloro-1-ethyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one with 1-(3-hydroxyphenyl)guanidine hydrochloride. 1H-NMR (DMSO-d6) δ: 1.46 (m, 3H, CH3), 4.49 (m, 2H, CH2), 6.39 (m, 1H, Ph-H), 7.07 (m, 1H, Ph-H), 7.20 (m, 2H, Ph-H and Ar—H), 7.77 (d, 1H, J=5.6 Hz, Pyrimidin-H), 8.18 (d, 1H, J=5.6 Hz, Ar—H), 8.37 (d, 1H, J=5.6 Hz, Pyrimidin-H), 8.41 (s, 1H, Ar—H), 9.23 (s, 1H, OH), 9.32 (s, 1H, NH). MS (ESI+) m/z 362.1670 (M+H)+

Provenance & Evidence