(E)-1-(7-chloro-1-ethyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one → 3-(4-(7-Chloro-1-ethyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-ylamino)benzenesulfonamide

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Prepared by treatment of (E)-1-(7-chloro-1-ethyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one and 3-guanidinobenzenesulfonamide hydrochloride. 1H-NMR (DMSO-d6) δ: 1.45 (t, 3H, J=7.2 Hz, CH3), 4.48 (t, 2H, J=7.2 Hz, CH2), 7.30 (m, 3H, Pyrimidin-H and NH2), 7.43 (m, 1H, Ar—H or Ph-H), 7.50 (t, 1H, J=7.6 Hz, Ph-H), 7.82 (d, 1H, J=5.6 Hz, Ar—H), 7.89 (m, 1H, Ar—H or Ph-H), 8.07 (m, 1H, Ar—H or Ph-H), 8.45 (d, 1H, J=5.6 Hz, Pyrimidin-H), 8.48 (s, 1H, Ar—H), 8.61 (s, 1H, NH). MS (ESI+) m/z 426.1490 (M+H)+.

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