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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1875429Generated: October 31, 2026

7-Chloro-1H-pyrrolo[2,3-c]pyridine → 6-Azaindole

https://huagongshe.com/reaction/1875429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-1H-pyrrolo[2,3-c]pyridineHCID 11435048—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product6-AzaindoleHCID 9219—

Reaction Steps

Hydrogenation of 7-chloro-1H-pyrrolo[2,3-c]pyridine (10 mmol) was carried out in the presence of Pd—C (10%) in EtOH (50 mL). After stirred at room temperature for 20 hrs, the mixture was filtered through a pad of celite 521. The residue was washed with EtOH several times. The filtrate was evaporated to yield 1H-pyrrolo[2,3-c]pyridine as brown oil. MS (ESI+) m/z 119.0657 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309550B2
Source datasetuspto-grants-2012_11
ORD IDord-14bda9465d9d4c029d652445dd2920fb
Source noteuspto-grants-2012_11