HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-1H-pyrrolo[2,3-c]pyridine → 6-Azaindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-1H-pyrrolo[2,3-c]pyridine | HCID 11435048 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-Azaindole | HCID 9219 | — |
Reaction Steps
Hydrogenation of 7-chloro-1H-pyrrolo[2,3-c]pyridine (10 mmol) was carried out in the presence of Pd—C (10%) in EtOH (50 mL). After stirred at room temperature for 20 hrs, the mixture was filtered through a pad of celite 521. The residue was washed with EtOH several times. The filtrate was evaporated to yield 1H-pyrrolo[2,3-c]pyridine as brown oil. MS (ESI+) m/z 119.0657 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309550B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-14bda9465d9d4c029d652445dd2920fb |
| Source note | uspto-grants-2012_11 |