(E)-3-(dimethylamino)-1-(1-propyl-1H-pyrrolo[2,3-c]pyridin-3-yl)prop-2-en-1-one → 3-(4-(1-Propyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-ylamino)benzenesulfonamide

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Prepared by treatment of (E)-3-(dimethylamino)-1-(1-propyl-1H-pyrrolo[2,3-c]pyridin-3-yl)prop-2-en-1-one and 3-guanidinobenzenesulfonamide hydrochloride as described above. 1H-NMR (DMSO-d6) δ: 0.89 (t, 3H, J=7.2 Hz, CH3), 1.91 (m, 2H, CH2), 4.36 (t, 2H, J=7.2 Hz, CH2), 6.56 (s, 2H, NH2), 7.34 (m, 2H, Pyrimidin-H and Ph-H), 7.44 (m, 1H, Ar—H or Ph-H), 7.91 (m, 1H, Ar—H or Ph-H), 8.33 (d, 1H J=5.2 Hz, Ar—H), 8.45 (d, 1H, J=5.6 Hz, Pyrimidin-H), 8.52 (m, 2H, Ar—H or Ph-H), 9.02 (s, 1H, Ar—H or Ph-H), 9.84 (s, 1H, Ar—H or Ph-H). MS (ESI+) m/z 409.1514 (M+H)+.

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