HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Bromoethoxy)tetrahydro-2H-pyran → HCID 11555149, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Bromoethoxy)tetrahydro-2H-pyran | HCID 86621 | — |
| Reactant | 1-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol | HCID 23992385 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 11555149 | HCID 11555149 | 31.6% |
Reaction Steps
Following the general procedure outlined in Example 4, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0696 g, 0.237 mmol) and 2-[(2-bromoethyl)oxy]tetrahydro-2H-pyran (0.080 mL, 0.529 mmol) in 2 CH3CN/3 CHCl3 (5.0 mL) were reacted to give the desired product (0.0348 g, 31.6%). EI-MS m/z 422 (M+) Rt (1.85 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309572B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-10304479e3984be2aadf2b3a71f04db6 |
| Source note | uspto-grants-2012_11 |