Dimethyl Sulfoxide → tert-Butyl 4-(1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-4-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-2-yl)piperidine-1-carboxylate
Reaction equation
[Br:27][CH2:28][CH2:29][O:30][CH:31]1[O:32][CH2:33][CH2:34][CH2:35][CH2:36]1.[CH3:37][S:38](=[O:39])[CH3:40].[K+:26].[O:1]1[CH2:2][CH2:3][CH:4]([c:7]2[n:8][c:9]([CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[nH:10][cH:11]2)[CH2:5][CH2:6]1.[OH-:25]>>[O:1]1[CH2:2][CH2:3][CH:4]([c:7]2[n:8][c:9]([CH:12]3[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[n:10]([CH2:28][CH2:29][O:30][CH:31]3[O:32][CH2:33][CH2:34][CH2:35][CH2:36]3)[cH:11]2)[CH2:5][CH2:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-af57c87959a44478ab1b14fa6dcd8d6e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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