2-Chlorobenzyl alcohol → 2-[2-(2-Chloro-benzyloxy)-pyridin-3-yl]-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole

Participants

Role	Name	HCID	Charge
Reactant	2-Chlorobenzyl alcohol	HCID 28810	—
Reactant	2-(2-chloro-pyridin-3-yl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole	HCID 86652286	—
Product	2-[2-(2-Chloro-benzyloxy)-pyridin-3-yl]-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole	HCID 58209249	—

Reaction Steps

The title compound was prepared in analogy to Example 1, from 2-(2-chloro-pyridin-3-yl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole (Ex. 1, intermediate a) and (2-chloro-phenyl)-methanol (CAS Reg. No. 17849-38-6). Light yellow solid (48%). MS (Turbo Spray): m/z=468.2 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08309581B2
Source dataset	uspto-grants-2012_11
ORD ID	ord-b8bedae4352a41788fc20455d3f13815
Source note	uspto-grants-2012_11