HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-Benzyl-2-(2-chloro-pyridin-3-yl)-5,6-difluoro-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 2-(2-Chloropyridin-3-YL)-5,6-difluoro-1H-benzo[D]imidazole | HCID 71741803 | — |
| Product | 1-Benzyl-2-(2-chloro-pyridin-3-yl)-5,6-difluoro-1H-benzoimidazole | HCID 86652287 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1, intermediate a, from 2-(2-chloro-pyridin-3-yl)-5,6-difluoro-1H-benzoimidazole and bromomethyl-benzene (CAS Reg. No. 100-39-0). Colorless solid (52%). MS (Turbo Spray): m/z=356.3 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-2de88540cdf44a35824de25ff5422075 |
| Source note | uspto-grants-2012_11 |