Cyclopentanemethanol → HCID 51042707, compound

HRID 1875729Notes

Reaction equation

HRID 1875729 reaction equation
[CH2:1]([N:8]1[C:12]2[CH:13]=[C:14]([F:18])[C:15]([F:17])=[CH:16][C:11]=2[N:10]=[C:9]1[C:19]1[C:20]([O:25][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29]C=2Cl)=[N:21][CH:22]=[CH:23][CH:24]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(CO)CCCC1>>[CH2:1]([N:8]1[C:12]2[CH:13]=[C:14]([F:18])[C:15]([F:17])=[CH:16][C:11]=2[N:10]=[C:9]1[C:19]1[C:20]([O:25][CH2:26][CH:27]2[CH2:29][CH2:30][CH2:31][CH2:32]2)=[N:21][CH:22]=[CH:23][CH:24]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 77195CyclopentanemethanolHCID 51042706HCID 51042706, compound

Product 1

HCID 51042707HCID 51042707, compound

Procedure

The title compound was prepared in analogy to Example 1, from 1-benzyl-2-(2-chloro-pyridin-3-yl)-5,6-difluoro-1H-benzoimidazole (Example 6, intermediate) and cyclopentyl-methanol (CAS Reg. No. 3637-61-4). Light yellow powder (42%). MS (Turbo Spray): m/z=419.9 (M+H).

Sources & evidence

ORD record
ord-21e77504128b42688fd2c526383d038f
Source dataset
uspto-grants-2012_11
Patent number
US08309581B2

Reaction notes

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