Acetic acid, 2-[4-(bromomethyl)phenoxy]-, methyl ester → {4-[5-Chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenoxymethyl]-phenoxy}-acetic acid methyl ester

Participants

Reaction Steps

The title compound was prepared in analogy to Example 5, intermediate a, from 5-chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenol (Example 19, intermediate a) and (4-bromomethyl-phenoxy)-acetic acid methyl ester (CAS Reg. No. 104508-23-8). Brown sticky solid (55%). MS (Turbo Spray): m/z=555.2 (M+H).

Provenance & Evidence