HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyano-3-fluorobenzyl bromide → HCID 67049976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyano-3-fluorobenzyl bromide | HCID 2778466 | — |
| Reactant | 5-chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenol | HCID 136378478 | — |
| Product | HCID 67049976 | HCID 67049976 | — |
Reaction Steps
The title compound was prepared in analogy to Example 5, intermediate a, from 5-chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenol (Example 19, intermediate a) and 4-bromomethyl-2-fluoro-benzonitrile (CAS Reg. No. 222978-03-2). Off-white powder (89%). MS (Turbo Spray): m/z=510.3 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-978ad70eef114b9b853a8a2d131c23d6 |
| Source note | uspto-grants-2012_11 |