O-Phenylenediamine → 2-(4-Chloro-2-methoxy-phenyl)-1H-benzoimidazole

HRID 1875768Notes

Reaction equation

HRID 1875768 reaction equation
[C:1]1([NH2:8])[C:2]([NH2:7])=[CH:3][CH:4]=[CH:5][CH:6]=1.[Cl:9][C:10]1[CH:18]=[CH:17][C:13]([C:14](O)=O)=[C:12]([O:19][CH3:20])[CH:11]=1>>[Cl:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]2[NH:8][C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=3[N:7]=2)=[C:12]([O:19][CH3:20])[CH:11]=1

Participants

3

Reactant 2

HCID 7243O-PhenylenediamineHCID 936824-Chloro-o-anisic acid

Product 1

HCID 617258442-(4-Chloro-2-methoxy-phenyl)-1H-benzoimidazole

Procedure

The title compound was prepared in analogy to Example 19, intermediate c, from benzene-1,2-diamine (CAS Reg. No. 95-54-5) and 4-chloro-2-methoxy-benzoic acid (CAS Reg. No. 57479-70-6). Colorless powder (59%). MS (Turbo Spray): m/z=259.4 (M+H).

Sources & evidence

ORD record
ord-0b999dc48d474b9facb04e90655a9a27
Source dataset
uspto-grants-2012_11
Patent number
US08309581B2

Reaction notes

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