(Bromomethyl)cyclopentane → HCID 58209244, compound

HRID 1875789Notes

Reaction equation

HRID 1875789 reaction equation
[CH2:1]([N:8]1[C:12]2[CH:13]=[C:14]([F:18])[C:15]([F:17])=[CH:16][C:11]=2[N:10]=[C:9]1[C:19]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:20]=1[OH:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:28][CH:29]1[CH2:33][CH2:32][CH2:31][CH2:30]1>>[CH2:1]([N:8]1[C:12]2[CH:13]=[C:14]([F:18])[C:15]([F:17])=[CH:16][C:11]=2[N:10]=[C:9]1[C:19]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:20]=1[O:26][CH2:28][CH:29]1[CH2:33][CH2:32][CH2:31][CH2:30]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 12723264(Bromomethyl)cyclopentaneHCID 136378483HCID 136378483, compound

Product 1

HCID 58209244HCID 58209244, compound

Procedure

The title compound was prepared in analogy to Example 19, from 2-(1-benzyl-5,6-difluoro-1H-benzoimidazol-2-yl)-5-chloro-phenol (Example 48, intermediate a) and bromomethyl-cyclopentane (CAS Reg. No. 3814-30-0). Colorless powder (33%). MS (Turbo Spray): m/z=453.0 (M+H).

Sources & evidence

ORD record
ord-9df627ee1aff45459432f6ff9e4a6ea7
Source dataset
uspto-grants-2012_11
Patent number
US08309581B2

Reaction notes

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